Kemp was not involved in any of the three ODIs during England's 3-0 clean sweep of the West Indies and has been suffering with back pain.
"England Women's all-rounder Freya Kemp has been ruled out of the rest of the West Indies series with back pain limiting her cricket," an ECB statement said.
"Kemp will now return to the UK for further exploratory scans."
England and West Indies play the first of five T20Is in Antigua on Sunday night. The final four games take place in Barbados from December 14-22.