Cardiff's international quartet of new signings are in line to be involved in Saturday's United Rugby Championship opener against Munster.
Full-back Liam Williams, number eight Taulupe Faletau and lock Lopeti Timani are set to make debuts.
Flanker Thomas Young begins a second stint after returning from Wasps.
Josh Adams, Tomos Williams, Dillon Lewis and Rhys Carre are also available after touring South Africa with Wales this summer.
Flanker Josh Navidi and number eight James Ratti miss out through injury, while fellow Wales back rower Ellis Jenkins is absent.