Minnesota Twins starting pitcher Joe Ryan exited Wednesday's 8-2 loss to the Chicago Cubs in the bottom of the third inning with right triceps tightness.

After throwing a pitch to Pete Crow-Armstrong, who was leading off the frame, Ryan motioned toward the dugout and was visited by Minnesota manager Rocco Baldelli and a trainer. He then left the game following a brief conference.

In his two-plus innings, Ryan gave up one run on one hit. He didn't issue a walk and struck out two. The Twins were leading 2-1 at the time.

Trevor Richards replaced Ryan and gave up three runs on a hit and five walks in of an inning.

Ryan entered Wednesday with a 7-7 record and a 3.59 ERA across 22 starts this season.