Championship clubs' exclusion from cup 'appalling'
Written by I Dig SportsChinnor's promotion means that the Championship will return to a 12-team league next season, following the demise of Jersey Reds last autumn.
Cambridge, who were promoted to the second tier for the first time in 2023, finished bottom of the table last season.
The club said they are now seeking compensation for a loss of income caused by missing out on the cup games.
"The decision was made based on a seeding basis," Cambridge chairman Tim Hague said.
"Whilst this is logical, its not really fair. As such we have asked for significant compensation to offset substantial income loss from both missing out on bumper Premiership fixtures and the consequent loss of home gates and hospitality income.
"The other issue is a seven-weekend hole in our fixture list, which means a lack of continuity and momentum."
The opening round of matches will feature a number of derbies, including Northampton hosting Leicester.
Elsewhere, Cornish Pirates are at home to Exeter Chiefs, Hartpury take on Gloucester, while Harlequins and Saracens travel to London Scottish and Ealing respectively.