EAST RUTHERFORD, N.J. -- Buffalo Bills running back James Cook is inactive for Monday night's game against the New York Jets with a toe injury suffered in last week's loss to the Houston Texans.

Cook was a limited participant in Saturday's practice, after not participating earlier in the week, and was listed with a questionable designation going into the game.

"It's getting better. Just improving every day," Cook said after Saturday's practice. "Trying to get it back stronger, and go out there and help the team, like I said, I'm just taking it day by day, treatment, see what, how I feel on Monday."

Without Cook available, the team has elevated rookie running back Frank Gore Jr. from the practice squad. This will be his first career game action. Running backs Ty Johnson and rookie Ray Davis are expected to take on a significant load in Cook's absence.

The Bills are looking avoid a three-game losing streak for the first time since 2018. While Cook is out along with defensive tackle Ed Oliver (hamstring), wide receiver Khalil Shakir (ankle), nickel cornerback Taron Johnson and defensive tackle Austin Johnson are all active after being designated as questionable. This will be Taron Johnson's first game since Week 1.