Irish rugby fans will not be treated to an intriguing fly-half duel between Leinster's Sam Prendergast and Munster's Jack Crowley with the latter set to miss Friday's United Rugby Championship interpro at Thomond Park (19:35 GMT).

Prendergast and Crowley have been battling for the Ireland 10 jersey with each player starting two of last month's Autumn Nations Series matches.

But while Prendergast, who was preferred for Ireland's two most recent wins over Fiji and Australia, starts for Leinster, Crowley has been ruled out because of Irish Rugby Football Union [IRFU] player management guidelines with Billy Burns named to start.

Crowley's absence is a further blow for Munster interim head coach Ian Costello, who is without several players amid a mounting injury list.

Earlier this week, Thaakir Abrahams (shoulder), Craig Casey (knee) and Jean Kleyn (thigh) were ruled out for approximately four months while Alex Nankivell (hamstring) is also unavailable.

In addition, Peter O'Mahony (calf contusion), Conor Murray (elbow) and Jack O'Donoghue (shoulder) have failed to regain their fitness in time for Friday's game.

Munster make seven changes from their win over Ulster in Belfast. Tadhg Beirne returns as captain, with Rory Scannell, Billy Burns, Ethan Coughlan, Dian Bleuler, Oli Jager and Alex Kendellen also recalled.

Fit-again Jamie Osborne Ireland back returns for Leinster after missing the last three games with the groin injury he sustained on international duty last month.

His inclusion is one of 11 changes made by head coach Leo Cullen, who has recalled Ireland internationals Prendergast, Robbie Henshaw and Garry Ringrose to his backline after last week's win over Connacht.

Ronan Kelleher, Gus McCarthy, James Ryan, Ryan Baird, Josh van der Flier and Caelan Doris are reinstated to the Leinster pack, but New Zealand international Jordie Barrett has not been included in the 23.

Springbok lock RG Snyman, who left Munster to join Leinster last summer, is also missing from Cullen's matchday squad.

Munster: Mike Haley; Calvin Nash, Tom Farrell, Rory Scannell, Shane Daly; Billy Burns, Ethan Coughlan; Dian Bleuler, Niall Scannell, Oli Jager; Fineen Wycherley, Tadhg Beirne (capt); Tom Ahern, Alex Kendellen, Gavin Coombes.

Replacements: Diarmuid Barron, Kieran Ryan, John Ryan, Brian Gleeson, John Hodnett, Paddy Patterson, Tony Butler, Ben O'Connor.

Leinster: Jamie Osborne; Tommy O'Brien, Garry Ringrose, Robbie Henshaw, Jimmy O'Brien; Sam Prendergast, Luke McGrath; Jack Boyle, Ronan Kelleher, Rabah Slimani; Joe McCarthy, James Ryan; Ryan Baird, Josh van der Flier, Caelan Doris (capt).

Replacements: Lee Barron, Andrew Porter, Cian Healy, Brian Deeny, Scott Penny, Fintan Gunne, Ross Byrne, Jordan Larmour.