Tasmania 78 and 4 for 72 trail Queensland 257 (Khawaja 56, Bird 4-68) by 107 runs
Tasmania's horror match with the bat continued at the Gabba as they lost three second-innings wickets without a run on the board to leave them facing an innings defeat against Queensland.
A battling half-century from Usman Khawaja and handy lower-order contributions had taken Queensland to a lead of 179 after they had dismantled Tasmania for 78 on the opening day.
In reply, Alex Doolan, Jordan Silk (who bagged a pair) and Jake Doran all fell for ducks against Michael Neser and Jack Wildermuth.
They regained some composure as Charlie Wakim and Ben McDermott added 72 but Wakim was pinned lbw by Mitchell Swepson late in the day.
Queensland were already in the lead overnight but Tasmania mounted something of a fightback as they chipped away. Bryce Street's 171-ball stay ended when he edged Jackson Bird and Sam Heazlett was given caught down the leg side.
Khawaja held the innings together with his second Shield half-century of the season before the hard work ended when a booming drive was edged to second slip. Cameron Gannon and Mark Steketee chipped in with 20s from Nos. 9 and 10. The innings was wrapped up by the offspin of Beau Webster who, in a game dominated by the seamers, finished with 3 for 44.