Barcelona's first team will return to training on Friday with players taking part in individual workouts, the club announced on Thursday.
Players will maintain sufficient space between each other stipulated by the health authorities and La Liga protocols. Players will arrive at the club facilities already in their training kit and will return straight home without visiting the changing rooms.
Spanish outlet RAC1 first reported that Barcelona players tested negative for the coronavirus, which was confirmed by ESPN.
Organising body La Liga said clubs in the top two divisions would resume training this week for the first time since activity was halted due to the coronavirus pandemic and targeted resuming the season in June.
"These measures cover a period of approximately four weeks with different phases that, in any case, will be subject to the de-escalation process established by the government," said the statement.
"Thus, together with the medical tests carried out by clubs, a staggered return to training has been implemented that will start with players training alone and with group activities prior to the return to competition, scheduled for June."
La Liga president Javier Tebas said the season would bring back a sense of normality to Spain, which has lost over 25,000 lives to the virus and seen its economy paralysed.
"This crisis has had a profound impact on all of us. The return of football is a sign that society is progressing towards the new normal. It will also bring back an element of life that people in Spain and around the world know and love," he said.
Germany's Bundesliga will return on May 16 and hope to complete the season by June 30. England's Premier League and Italy's Serie A have also gradually implemented individual training regimes. The French, Dutch, and Belgian leagues have all cancelled.
Information from Reuters used in this report.