Ireland and Munster fly-half Joey Carbery faces a long spell on the sidelines after a setback in his recovery from ankle surgery.
The 24-year-old had already been ruled out for the season after the operation in February - Carberry sustained the injury six months earlier.
Munster announced on Tuesday that Carbery would not be available "for an indefinite period of time".
"I'll be back better than ever. I just need time right now," said Carbery.
The number 10 picked up the ankle injury during Ireland's World Cup warm-up game against Italy last August.
He added: "It's an incredibly frustrating time at the moment, but I am making good progress over the last couple of weeks.
"Even though the ankle isn't where it needs to be just yet, I've full confidence it will heal and be pain-free soon.
"I'm so excited to get back out in front of the fans. It's going to be such an exciting season ahead and I cannot wait to see where we can go as a squad. Hopefully, we will all be back in Thomond Park soon together."