Wales prop Rob Evans will make his first Pro14 start of the season when Scarlets take on Zebre on Sunday.
Evans has made replacement appearances after recovering from neck surgery and comes in for Phil Price at loose-head in one of three changes to the team narrowly beaten by Edinburgh.
Lock Jac Price comes in for suspended second-row Josh Helps, while wing Ryan Conbeer replaces Tyler Morgan.
Scarlets have lost three out of their four league games so far this season.
There are a number of changes on the replacements' bench with prop Kemsley Mathias and fly-half Sam Costelow poised to make league debuts.
Danny Drake, recently recalled from a loan spell at Gloucester, goes straight into the matchday 23 to provide second-row cover.
"We want to go out and execute an 80-minute performance," said Scarlets attack coach Richard Whiffin.
"We have shown in parts our ambition to play, our defence has been outstanding. Obviously we know we need to sharpen up on our discipline. If we can nail those three things, hopefully we can get on the right side of the result."
Scarlets: Johnny McNicholl; Ryan Conbeer, Steff Hughes (capt), Paul Asquith, Steff Evans; Angus O'Brien, Dane Blacker; Rob Evans, Taylor Davies, Javan Sebastian, Jac Price, Morgan Jones, Uzair Cassiem, Jac Morgan, Sione Kalamafoni.
Replacements: Dom Booth, Kemsley Mathias, Werner Kruger, Danny Drake, Ed Kennedy, Will Homer, Sam Costelow, Tyler Morgan.
Zebre: Junior Laloifi; Pierre Bruno, Giulio Bisegni (capt), Tommaso Boni, Giovanni D'Onofrio; Antonio Rizzi, Joshua Renton; Paolo Buonfiglio, Marco Manfredi, Eduardo Bello, Leonard Krumov, Ian Nagle, Nardo Casolari, Antoine Koffi, Lorenzo Masselli.
Replacements: Oliviero Fabiani, Andrea Lovotti, Matteo Nocera, Gabriele Venditti, Massimo Ceciliani, Nicolo Casilio, Enrico Lucchin, Michelangelo Biondelli.
Referee: Sean Gallagher (IRFU)
Assistant Referees: Craig Evans, Gwyn Morris (WRU)
TMO: Wayne Davies (WRU).