Mets right-hander Jacob deGrom tied Nolan Ryan's record for most strikeouts through a pitcher's first five starts of a season, finishing Wednesday night's start with nine strikeouts over six innings to run his five-game total to 59. But deGrom did so in a losing cause, as New York fell 1-0 to the Boston Red Sox at Citi Field.

It was deGrom's 33rd career start, and third in 2021, in which he allowed one run or fewer and failed to pick up the win, most in the majors since he made his debut in 2014. Julio Teheran has the second-most such starts over that time frame with 25.

DeGrom has made 81 career starts of six-plus innings in which he has allowed no more than one run, but only 48 of those resulted in wins (59%). The MLB average win rate over the past five seasons when pitching at least six innings with one or no runs is 69%.

DeGrom said the lack of run support wasn't on his mind Wednesday, saying he was "more disappointed that I wasn't able to make pitches" in the second inning, when he allowed the game's only run after doubles by Xander Bogaerts and Christian Vazquez.

"Everybody's out there giving 100 percent. Nobody wants to get out," deGrom said of the Mets' offense. "Those guys try to put together the best at-bats, I try to throw the ball to the spot for that pitch. They're competing. Sometimes you just have to tip your cap to the other team, and they did a nice job keeping our guys off-balance."

Manager Luis Rojas also threw his support behind his offense.

"We have nothing but trust in our hitters, because we know they can hit," Rojas said. "We know what they've done in the past. You expect that to happen soon, but it's something that we need to go and turn around right now."

After striking out 14, 14 and 15 batters in his previous three starts, deGrom was a little less dominant Wednesday night. Opposing starter Nick Pivetta even battled him for a 10-pitch at-bat, the most pitches deGrom has thrown to a pitcher and the most he has thrown to a batter this season. Still, deGrom has fanned 48.0% of the batters he has faced this season.

DeGrom finishes April with a 0.51 ERA. It's the 279th instance since earned runs became an official statistic in 1913 in which a pitcher had at least 55 strikeouts in one month, but deGrom ERA's is the lowest of the 279, beating Pedro Martinez's 0.64 ERA from July 2002.

In 1978, Ryan began his season with the California Angels with strikeout totals of 13, 12, 8, 15 and 11, finishing with 59 over 41 innings. Ryan also walked 25 batters, whereas deGrom walked four.

Ryan also faced some hard-luck run support, however. He had a 1.98 ERA in his five starts but won just one game, as he had a six-inning outing and a 10-inning outing in which he allowed no runs but received a no-decision.

The all-time record for strikeouts over any five-game stretch is Martinez's 72 in late 1999, when he recorded totals of 15, 11, 15, 17 and 14. Those five starts were bookended by games of 11 and then 12 and 12, giving Martinez a remarkable eight-game stretch of 107 K's over 62 innings.