CHICAGO -- Detroit Tigers starter Matthew Boyd left the second game of Thursday's doubleheader against the Chicago White Sox after facing seven batters because of an injured left knee.

With the score 0-0, the 30-year-old left-hander walked Yasmani Grandal leading off the second and gave up a double to Andrew Vaughn on his 36th pitch, a drive to the gap in left-center.

Boyd signaled to the dugout with a 1-1 count to Leury García, and manager A.J. Hinch and an athletic trainer went to the mound. Boyd then left the game.

Michael Fulmer relieved and allowed RBI singles to García and Nick Madrigal. then gave up a two-run single to José Abreu with two outs that put Chicago ahead 4-0.

Boyd's ERA rose from 1.82 to 2.27 with his one-inning outing.